The Purification Chamber is a device that can turn ores into ore clumps. For example: you could transform copper ore into 3 copper clumps. Not all ores can be transformed into clumps, these are the only ones that do and their transformation outcome:
The Purification Chamber needs an input of 120 Volt to work. It can also be powered by a battery (using the green slot with a power sign under it). An upgrade can be put in as well using the orange slot (top left). To give some sort of 'power' to the Purification Chamber you need to put Flint in the small blue slot (bottom). And last but not least, put your desired ore into the red slot (top). Your clumps will be ready for pickup in the large blue slot on the right side of the GUI.
The Purification Chamber can also be charged with Redstone Dust instead of using electricity (120V). It does take quite a heavy amount of Redstone Dust in order to turn ores into clumps: you need to put at least 4 Redstone Dust in the machine in order to transform one ore.
There are much different ways to craft a Purification Chamber but here's the most common way:
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